NVP-BEZ235 inhibits thyroid cancer growth by p53- dependent/independent p21 upregulation
نویسندگان
چکیده
منابع مشابه
Utility of a PI3K/mTOR Inhibitor (NVP-BEZ235) for Thyroid Cancer Therapy
BACKGROUND We assessed the utility of the dual PI3K/mTOR inhibitor NVP-BEZ235 (BEZ235) as single agent therapy and in combination with conventional chemotherapy for thyroid cancer. METHODOLOGY/PRINCIPAL FINDINGS Eight cell lines from four types of thyroid cancer (papillary, follicular, anaplastic, medullary) were studied. The cytotoxicity of BEZ235 and five conventional chemotherapeutic agent...
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ژورنال
عنوان ژورنال: International Journal of Biological Sciences
سال: 2020
ISSN: 1449-2288
DOI: 10.7150/ijbs.37592